In my project, I work on the LCMS-based microbial metabolomics.
Metabolomics deals with the qualitative and quantitative analysis of the metabolome, the body of small molecules (<1300 Da) made by a living cell. Hence, metabolomics can give an instantaneous snapshot of a biological sample.
The model organism Saccharomyces cerevisiae var. boulardii is a variant of baker’s yeast, but unlike baker’s yeast, S. boulardii is used worldwide to treat a range of gastrointestinal disorders. However, the mechanisms behind the biotherapeutic effects are largely unknown. By comparing the metabolome of the two yeast strains, metabolites that contribute to the special properties of S. boulardii may be elucidated.
During my PhD, I will establish a robust metabolomics workflow in the Schulz lab, and using this workflow I will investigate the metabolome of different microorganisms.
2019 Started PhD studies in Metabolomics, Ruhr University, Bochum, Germany
2018 Master of Science MSc in Chemistry and Molecular Biology, Roskilde University, Denmark
2016 Bachelor of Science BSc in Chemistry and Molecular Biology, Roskilde University, Denmark
Westh, P. Borch, K. Sørensen, T. Tokin, R. Kari, J. Badino, S. Cavaleiro, M. Røjel, N. Christensen, S. Vesterager, C. Schiano-di-Cola, C. “Thermoactivation of a cellobiohydrolase” Biotechnology and Bioengineering, January 2018
Pedersen, K. Elsalhi, H. Khoury, R. Thorsted, P. Vesterager, C. Hvidt, S. “Rapid Determination of endo- and exo cellulases” Nordic Rheology Society. Annual Transactions, 2016, Vol 24, p 103-109.
Fakultät für Chemie und Biochemie