Unlocking the vast potential of nature's molecular treasures, our research explores the synergies between engineered biosynthesis, enzyme catalysis, and organic synthesis, which collectively serve as powerful toolboxes for accessing and derivatizing natural products. We integrate metabolomics as an emerging and invaluable toolbox, enabling the identification of natural products and biosynthetic intermediates with unprecedented precision. This toolbox is also used to identify biomarkers in clinical settings and identify bioactive compounds in probiotics.
We optimize the bioactivity of small molecules derived from nature. This optimization is a pivotal step in our quest for novel antibiotics and anti-cancer activities. By harmonizing traditional methodologies with state-of-the-art techniques, we strive to push the boundaries of what is achievable in drug discovery.
Join us on this journey, where the fusion of diverse methodologies converges to unveil the untapped potential of natural compounds. In our dynamic research environment, you will have the opportunity to contribute to the development of cutting-edge solutions for pressing health challenges, propelling the field of natural product-based drug discovery to new heights.
We are a team of chemists, biochemists, and biologists, united in the pursuit for novel medicinally active small molecules.
We investigate novel strategies and methods towards the identification and derivatization of compounds from natural sources.
Undergraduate research projects: We offer projects for talented and motivated undergraduate students in chemistry, biochemistry.
Lectures: We teach organic chemistry, natural product chemistry, enzyme biochemistry and genetics
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Fakultät für Chemie und Biochemie