Natural product chemistry, chemoenzymatic synthesis of bioactive molecules:
Investigation of new strategies and methods to manipulate microbial biosynthetic pathways; selective chemical derivatisation of polyketides; microbial and chemoenzymatic synthesis of terpenoids; enzyme engineering.
10/2013, ongoing Professor of Organic Chemistry; Ruhr University Bochum, Faculty of Chemistry and Biochemistry.
10/2009 – 09/2013 Beilstein Professor of Bioorganic Chemistry at the Faculty of Chemistry, TU Dortmund, Germany
10/2008 – 09/2013 Group leader at the Max Planck-Institute of Molecular Physiology, Department of Chemical Biology (Professor H. Waldmann), Dortmund, Germany
06/2007 – 09/2008 University of Cambridge, Department of Biochemistry; postdoc with Professor P. F. Leadlay. Topic: „Alteration of Polyketide Synthase stereospecificity by enzyme engineering in S. erythraea”
01/2004 – 04/2007 Max-Planck-Institute of Coal Research under supervision of Professor M. T. Reetz, Topic: „Monooxygenases – Experiments to turn a class of enzymes into a toolbox for biocatalysis”.
10/1998 – 09/2003 Ruhr University Bochum, Germany, and University of Michigan, Ann Arbor, USA; Chemistry.
05/2013 JSP fellowship for the 48th Euchem Conference on Stereochemistry (Bürgenstock Conference)
12/2011 Thieme Chemistry Journals Award 2012
06/2008 Otto Hahn Medal of the Max Planck Society
06/2007 DSM Science & Technology Award 2007, Brussels.
Stipends and start-up funding
2008 - 2011 Liebig-stipend from the Foundation of the German Chemical Industry (Fonds der Chemischen Industrie).
2009 - 2013 Beilstein-Professorship, funded through the Beilstein Institute Foundation.
Fakultät für Chemie und Biochemie